Peyote Cactus

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Lophophora williamsii), commonly referred to as peyote cactus, has long been utilized by Native American religions for spiritual growth and healing purposes. How do I find the right peyote cactus for sale?

Mexico law protects this plant, while in the U.S., due to its hallucinogenic effects, it has been classified as a Schedule 1 drug and therefore restricted.


In 2005, radiocarbon dating and alkaloid analysis of two archaeological specimens of peyote buttons (Lophophora Williamsii) dating from prehistoric periods were performed. These analyses provided evidence for the prehistoric age of these samples.

Bernardino de Sahagun wrote the first reference to peyote in 1870 in his book Problemas y Secretos Maravillosos de las Indias (Problems and Miraculous Secrets of Indians). However, its botanical name wasn’t given until much later – in about the 1800s.

Charles Lemaire, of French botanist fame, first described peyote under its binomial Echinocactus Williamsii; however, his description did not contain an illustration. Since then, various collectors and horticulturists have identified multiple forms and varieties of peyote using various vegetative features, such as the number and prominence of ribs, color variations, or even trichomes, to identify proposals.


Lophophora williamsii is a button-shaped cactus with low, rounded sections known as peyote buttons that lack spines. It is found naturally throughout Mexico and parts of Texas, where many Indigenous cultures consider it sacred. Unfortunately, the Drug Enforcement Agency (DEA) restricts its use due to its hallucinogenic effects.

Cacti grow best in harsh conditions with total sunlight exposure. However, in difficult soil, so when cultivating peyotes for gardening, they must resemble their natural habitat as closely as possible to ensure healthy plants.

The Church is lobbying Congress to allocate funding for protecting peyote habitats. Wild populations of peyote plants have been declining due to over-harvesting; if demand continues, it could be listed as an endangered species.


Lophophora williamsii is a small cactus with a small hemispherical shape that produces mescaline, a hallucinogenic substance native to Mexico and the southwestern United States but now widely cultivated around the world.

Peyote grows best under conditions that replicate those found in its native desert environment and does not respond well to overly indulgent treatments. Therefore, during winter, it must remain dry, while during summer, it should be placed inside a warm greenhouse for optimal conditions.

Wild peyotes take fifteen to twenty-five years to reach full flowering maturity; under controlled conditions, this process can be expedited through grafting. To propagate a peyote cactus, slice off one button and put it in a pot filled with well-packed cacti mix until a scab forms over its cutting scar. Subsequently, plant it with its base down into fertile soil for six months until fully established.


Peyote, commonly called mescal button cacti, are native to Mexico and the southern U.S. and have long been utilized by Native American communities for spiritual and ceremonial use. Peyote contains psychoactive alkaloids such as mescaline that produce hallucinogenic effects when consumed.

Lophophora williamsii reproduces sexually, depositing its ovules into a fruit that ripens in summer and then bursts open after a year to release numerous tiny black seeds that are eventually spread by wind or rain.

Peyote plants can be grown indoors with minimal conditions; however, it requires warm and sunny surroundings for best results. Furthermore, possessing or cultivating peyote may be illegal without approval from a Native American Church or the Drug Enforcement Administration, as it falls into Schedule 1 status.


Peyote Cactus in the U.S. is illegal to cultivate without belonging to the Native American Church; however, numerous look-a-likes may be grown at home as an alternative. Peyote contains nine narcotic alkaloids, which cause hallucinations and auditory changes.

Peyote cacti require particular conditions to thrive, which can be challenging. For example, they need bright indirect sunlight, well-draining soil, and dry conditions – otherwise, pests and diseases could invade their plants quickly.

Peyote is a slow-growing plant that requires several years to become mature. To accelerate this process, graft it onto a rootstock such as Trichocereus Pachanoi or T. Bridgessii stem and attach its cutting directly on top. Hold onto the rope as soon as it is placed firmly onto the graft; soon afterward, peyote will grow around it!

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